Chemical Name:GS-441524
CAS:1191237-69-0
Synonyms; GS-441;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile;(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile;(2R,3R,4S,5R)-2-(4-AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLANE-2-;NUC;Remdesivir intermediates;GS-4;EVO984;GS441525;S-441524
CBNumber:CB04808604
Molecular Formula:C12H13N5O4
Molecular Weight:291.26
MDL Number:MFCD32666994
Melting point；> 233° C (dec.)
Density；1.84±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility；Soluble in DMSO (>25 mg/ml)
pka；12.13±0.70(Predicted)
Appearance;White powder,tablet,liquid
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Application
Introduction
GS-441524 is the biologically active component of Remdesivir and has been widely used around the world to safely and effectively cure cats of feline infectious peritonitis (FlP) for over 18 months. FIP is a common and highly fatal disease of cats.
Function
GS-441524 is a small molecule with a scientific name of nucleoside triphosphate competitive inhibitor, which shows strong antiviral activity against many RNA viruses. It serves as an alternative substrate and RNA chain terminator for viral RNA-dependent RNA polymerase. The non-toxic concentration of GS-441524 in feline cells is as high as 100, which effectively inhibits FIPV replication in CRFK cell culture and naturally infected cat peritoneal macrophages with a concentration .

Why Choose Us? 

1. Selecting raw materials strictly,our products are the highest purity.

2. Reasonable and competitive price. Provide the best and professional service.

3. Fast delivery of the samples ,samples from stock. Reliable shipping way.

4. Full experience of large numbers containers loading in Chinese sea port.

5. Best after-service after shipment .

6. Professional documents for your custom clearance.  

FAQ

Q1:Are you trading company or manufacturer?

A1: We are chemical factory in China. So we can provide wholesale price and product customization.

Q2: How to confirm the product quality before placing an order?

1) You can get free samples of some products, just pay the basic fee for us.

2) You can also send us the specifications or your requirements, and we will customize the product for you.

Q3: How long is your delivery time?

A3: Generally 1-3workkdays after order confirmed.

Q4: what's your terms of payment?

A4: We can accept various payment methods, western union, T/T, BTC( bitcoin)etc.

Shipping and payment